Medical Products Supplies Companies

Rudolf-Baschant-Str. 2, 13086 Berlin
Germany
Telephone +49 30 912078-0
Fax +49 30 912078-11
mail@poly-an.de
http://www.poly-an.de

Product Categories

Product categories

05 Commodities and Consumer Goods
05.07 Disposables
05.07.02 Disposable articles for laboratories

Disposable articles for laboratories

Functionalized Glass Slides
Functionalized Polymer Slides
Functionalized Coverslips
Functionalized PMMA microparticles (beads)
PMMA Nanoparticles
Reactive microplates for immunoassays

Our products

Product category: Disposable articles for laboratories
Functionalized Glass Slides
2D-functionalized Glass Slides

For cost-sensitive applications PolyAn has developed a range of 2D (2-dimensional)-reactive glass slides that are manufactured from high quality glass with an ultra-flat surface and low inherent fluorescence. The glass is coated with a thin silane layer that will covalently bind most types of bio-molecules. The defect-free surface features uniform silane layers that provide a high covalent coupling efficiency together with a very low background. The slides are easy to use, and are fully compatible with all commercially available arraying and scanning instruments.

3D-functionalized Glass Slides

PolyAn’s 3D-functionalised microarray Slides are functionalized with a three-dimensional (3D)-surface chemistry comprised of a long-chain polymer containing a defined number of reactive groups. This polymer is covalently linked to the surface of the slide.

Our MSE-technology gently binds the functional layer onto the surface without damaging the base substrate. The morphology of the functional surface and thus the number of the reactive groups can be fine-tuned within a narrow range. This yields a number of advantages:

Low fluorescence background: Covalent binding of functional layer on the substrate without changing the initial autofluorescence.
Low unspecific binding: Combination of reactive functional groups with PolyAn antifouling matrix.
Topography:Tuneable surface,hydrophilicity / hydrophobicity (contact angle).
Uniform spot morphology: Narrow variation of surface properties and homogeneous distribution of reactive groups.
Optimal density and high accessibility of reactive groups: Morphology and thickness of functional layer tailored to the desired application.

Product category: Disposable articles for laboratories
Functionalized Polymer Slides
Especially for diagnostic applications PolyAn is offering a broad range of functionalized microarray polymer slides. For reasons of reliability and bio-safety, patient-centric biomarker testing is always performed in single-use cartridges with a one-step process (sample in – result out). These cartridges should be disposable after use, so the materials of the cartridge should be non-hazardous and recyclable.

PolyAn’s Polymer Slides are comprised of a low auto fluorescence plastic. The material is highly robust against breakage making it the material of choice when working with hazardous materials. It is suitable for injection molding and hot embossing processes.

The slides are produced with standard dimensions of 25 x 75 x 1 mm. Additionally, we offer the functionalization of your plastic including microfluidics with a surface modification that is tailored to your specific application. Please also have a look at our ProPlate, HybriWell and SecureSeal products that facilitate handling of slides.

3D-reactive Polymer Slides

PolyAn’s 3D-functionalised microarray Slides are functionalized with a three-dimensional (3D)-surface chemistry comprised of a long-chain polymer containing a defined number of reactive groups. This polymer is covalently linked to the surface of the slide.

Our MSE-technology gently binds the functional layer onto the surface without damaging the base substrate. The morphology of the functional surface and thus also the number of the reactive groups can be fine-tuned within a narrow range. This yields a number of advantages:

Low fluorescence background: Covalent binding of functional layer on the substrate without changing the initial autofluorescence.
Low unspecific binding: Combination of reactive functional groups with PolyAn antifouling matrix.
Topography: Tuneable surface, hydrophilicity / hydrophobicity (contact angle).
Uniform spot morphology: Narrow variation of surface properties and homogeneous distribution of reactive groups.
Optimal density and high accessibility of reactive groups: Morphology and thickness of functional layer tailored to the desired application.

Product category: Disposable articles for laboratories
Functionalized Coverslips
For high-resolution microscopic imaging or scanning applications PolyAn offers functionalized coverslips. All of PolyAn’s standard functional coatings can also be applied to coverslip glass. All coverslips have the standard dimension of 25 x 60mm. Type #1.5 is used as a standard thickness. All coverslips are packed in boxes of 5. Other functionalities and formats are available upon request. PolyAn also offers functionalised substrates that are coated with gold or other noble metals as well as waveguide materials.

2D-functionalized Coverslips

For cost-sensitive applications PolyAn has developed a range of 2D (2-dimensional)-reactive coverslips that are manufactured from high quality glass with an ultra-flat surface and low inherent fluorescence. The glass is coated with a thin silane layer that will covalently bind most types of bio-molecules. The defect-free surface features uniform silane layers that provide a high covalent coupling efficiency together with a very low background.

3D-functionalized Coverslips

PolyAn’s 3D-functionalised microarray Slides are functionalized with a three-dimensional (3D)-surface chemistry comprised of a long-chain polymer containing a defined number of reactive groups. This polymer is covalently linked to the surface of the coverslip.

Product category: Disposable articles for laboratories
Functionalized PMMA microparticles (beads)
PolyAn is offering a portfolio of monodisperse PMMA (poly methyl methacrylate) particles for multiplex bead assays, calibration of flow cytometers and calibration of fluorescence imaging systems as well as a wide range of other applications in LifeScience research. PolyAn’s non-porous particles are comprised of a PMMA core with a 3D surface modification:

Transparent PMMA beads (microparticles)
Functionalized, transparent PMMA beads (microparticles)
Fluorescence encoded beads for standardisation and calibration
Functionalized fluorescence encoded beads
Fluorescence encoded beads for multiplex bead assays
Calibration slide for fluorescence imaging systems
Fluorescence lifetime encoded beads

PolyAn’s microparticles can be colour encoded with up to six fluorescent dyes. The fluorophores are directly incorporated into the core of the bead during the microparticle formation. This ensures a much more homogeneous distribution of the dyes within the beads when compared to conventional diffusion controlled dyeing processes.

PolyAn’s microparticles are functionalized using our proprietary Molecular Surface Engineering (MSE) Technology. PolyAn’s reactive matrices are suitable as a platform for a wide range of coupling methods. Our microparticles are characterized by low non-specific adsorption and low aggregation behaviour.

Product category: Disposable articles for laboratories
PMMA Nanoparticles
Our PMMA (Polymethylmethacrylate) based nanospheres are available in sizes between 100 nm to 500 nm. They are characterized by a narrow particle size distribution and an excellent lot-to-lot reproducibility. PMMA submicron beads are biocompatible und thus suited for live cell applications. Latex beads with carboxy and aldehyde for immobilization of biomolecules (proteins, antibodies, haptens, etc.) as well as plain beads are available.

Product category: Disposable articles for laboratories
Reactive microplates for immunoassays
PolyAn´s reactive microplates are beneficial for immobilizing biomolecules that inefficiently coat by passive adsorption. PolyAn offers amine-binding and nucleophilic binding surfaces as well as 3D-Azide plates for bio-orthogonal binding via click-chemistry.

Key features

Reactive surfaces for covalent immobilization ensure minimal leaching
Withstands rigorous washing
Minimal unspecific binding due to 3D functional matrix
Control of orientation of the probe to be immobilized and even directed (bio-orthogonal) immobilization possible

Available surfaces

3D-Epoxy for nucleophilic binding
3D-NHS for amine-binding
3D-Azide for click chemistry applications
Streptavidin
Neutravidin

The plates are offered for colorimetric, chemiluminescence and fluorescent detection systems, respectively. PolyAn also offer glass bottom plates with a wide range of surfaces and well designs as well as functionalized, solvent stable microplates that are comprised of Polypropylene (PP).

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About Us

Company details
Molecular Surface Engineering since 1996

PolyAn is a nanotechnology company specialized in the modification of surfaces using Molecular Surface Engineering (MSE). Since 1996 PolyAn develops and manufactures high performance consumables for multiplex diagnostics and LifeScience research.

PolyAn is certified according to DIN ISO 9001. PolyAn’s production facilities also include a class 7 cleanroom.

Microarrays
PolyAn is one of the leading producers of functionalized substrates for microarrays. Our wide range of surfaces, substrates and handling tools for microarrays enables our customers to easily select the most suitable substrate for their specific application.

Our product portfolio includes both functionalized glass slides as well as ultra-transparent plastic slides, coverslips, reactive membranes and 96-well microplates. Available surfaces for immobilization of biomolecules range from simple 2D-silanes, 3D-reactive nanogels and hydrogels to matrices for bio-orthogonal coupling via click-chemistry. Additionally, PolyAn is the European distributor of the nitrocellulose film slides and microarray accessories of Grace Bio-Labs.

Microparticles
PolyAn is offering a portfolio of monodisperse poly methyl methacrylate (PMMA) microparticles (beads) for multiplex bead assays, calibration of flow cytometers and calibration of fluorescence imaging systems. PolyAn’s microparticles can be colour encoded with a wide range of fluorescent dyes and functionalized with PolyAn reactive 3D-matrices.

Functionalized microplates
PolyAn´s microplates are used for covalently immobilizing biomolecules that inefficiently coat by passive adsorption. PolyAn offers Amine binding, 3D-Azide and Streptavidin coated 96-well plates for challenging ELISA applications.

Calibration tools for fluorescence imaging systems
Re-usable calibration tools for fluorescence based detection systems. PolyAn’s calibration slides for cell assays can be used as quality controls in a number of IVD systems for immunology applications.

Molecular Surface Engineering Services
PolyAn is able to equip almost any substrate with our reactive matrices for selective immobilization and antifouling surfaces for the reduction of cell adhesion and unspecific binding, respectively. As part of our Molecular Surface Engineering services, we offer functionalized consumable and substrate materials for OEM applications, which are tailored to specified customer requirements.

Company data
Foundation

1996

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